2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Protein (Entity type)	IC50
2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	cGMP-specific 3',5'-cyclic phosphodiesterase Protein (Entity type)	IC50
2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A Protein (Entity type)	IC50
2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Impotence Disease or Phenotype (Entity type)
2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Protein (Entity type)	IC50

2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Protein (Entity type)
IC50

2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
cGMP-specific 3',5'-cyclic phosphodiesterase
Protein (Entity type)
IC50

2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Protein (Entity type)
IC50

2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Impotence
Disease or Phenotype (Entity type)

2-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein (Entity type)
IC50

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