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Toloxatone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Toloxatone's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Toloxatone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Riociguat Compound (Entity type)	0.1824956089258194
	Toloxatone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NDE1 Gene (Entity type)	0.0046623945
	Toloxatone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RAB38 Gene (Entity type)	-0.0048559946
	Toloxatone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Amine oxidase [flavin-containing] A Protein (Entity type)	IC50
	Toloxatone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NUSAP1 Gene (Entity type)	0.0045010154
	Toloxatone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNS3 Gene (Entity type)	-0.004522741
	Toloxatone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COQ8A Gene (Entity type)	0.004815235
	Toloxatone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PENK Gene (Entity type)	0.004426362
	Toloxatone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TES Gene (Entity type)	-0.0066275317
	Toloxatone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LMO2 Gene (Entity type)	0.006196401

Toloxatone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Riociguat
Compound (Entity type)
0.1824956089258194

Toloxatone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NDE1
Gene (Entity type)
0.0046623945

Toloxatone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RAB38
Gene (Entity type)
-0.0048559946

Toloxatone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Amine oxidase [flavin-containing] A
Protein (Entity type)
IC50

Toloxatone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NUSAP1
Gene (Entity type)
0.0045010154

Toloxatone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNS3
Gene (Entity type)
-0.004522741

Toloxatone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COQ8A
Gene (Entity type)
0.004815235

Toloxatone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PENK
Gene (Entity type)
0.004426362

Toloxatone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TES
Gene (Entity type)
-0.0066275317

Toloxatone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LMO2
Gene (Entity type)
0.006196401

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