(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRG6 Gene (Entity type)	0.0035813716
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPX2 Gene (Entity type)	0.0035269205
deoxycorticosterone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	0.2269032150506973
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PDGFC Gene (Entity type)	-0.004256456
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	0.004522898
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF1AY Gene (Entity type)	0.0055664363
rac-Azelastine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	0.2882764041423797
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FABP1 Gene (Entity type)	0.003551333
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent serotonin transporter Protein (Entity type)	Ki
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OLFM1 Gene (Entity type)	0.0035579042

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRG6
Gene (Entity type)
0.0035813716

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPX2
Gene (Entity type)
0.0035269205

deoxycorticosterone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
0.2269032150506973

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PDGFC
Gene (Entity type)
-0.004256456

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFPI
Gene (Entity type)
0.004522898

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF1AY
Gene (Entity type)
0.0055664363

rac-Azelastine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
0.2882764041423797

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FABP1
Gene (Entity type)
0.003551333

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent serotonin transporter
Protein (Entity type)
Ki

(+/-)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol; Mazindol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OLFM1
Gene (Entity type)
0.0035579042

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