N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RAB11FIP1 Gene (Entity type)	-0.0038060325
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SEC24D Gene (Entity type)	0.0046519227
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	cyclosporin-a Compound (Entity type)	0.6163434386253357
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAF Gene (Entity type)	-0.004542193
mifepristone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	0.2982446849346161
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Bcl-2-like protein 2 Protein (Entity type)	Ki
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	YARS1 Gene (Entity type)	0.0046938327
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	0.005589391
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HYOU1 Gene (Entity type)	0.0048927558
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLEC2B Gene (Entity type)	-0.0044625048

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RAB11FIP1
Gene (Entity type)
-0.0038060325

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SEC24D
Gene (Entity type)
0.0046519227

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
cyclosporin-a
Compound (Entity type)
0.6163434386253357

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAF
Gene (Entity type)
-0.004542193

mifepristone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
0.2982446849346161

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Bcl-2-like protein 2
Protein (Entity type)
Ki

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
YARS1
Gene (Entity type)
0.0046938327

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
0.005589391

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HYOU1
Gene (Entity type)
0.0048927558

N-{4-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-benzoyl}-4-((S)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLEC2B
Gene (Entity type)
-0.0044625048

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