2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RARRES1 Gene (Entity type)	-0.0037493997
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FABP4 Gene (Entity type)	-0.003749586
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.004819592
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FAP Gene (Entity type)	0.0034768167
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.0039441455
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KCNJ16 Gene (Entity type)	-0.0037325986
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL5 Gene (Entity type)	-0.005278622
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	APOE Gene (Entity type)	0.0033405654
miglustat Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	0.4194990992546081
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-1 angiotensin II receptor Protein (Entity type)	Ki