4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	-0.0029908998
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DEGS1 Gene (Entity type)	-0.0029735526
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	-0.002968525
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARG1 Gene (Entity type)	0.0035216457
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MGP Gene (Entity type)	0.003247755
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Protein (Entity type)	Ki
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FBN2 Gene (Entity type)	-0.0034800812
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYBA Gene (Entity type)	0.0036584756
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF586 Gene (Entity type)	-0.0036104966
4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLCB1 Gene (Entity type)	0.0032282213

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
-0.0029908998

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DEGS1
Gene (Entity type)
-0.0029735526

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
-0.002968525

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARG1
Gene (Entity type)
0.0035216457

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MGP
Gene (Entity type)
0.003247755

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
Protein (Entity type)
Ki

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FBN2
Gene (Entity type)
-0.0034800812

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYBA
Gene (Entity type)
0.0036584756

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZNF586
Gene (Entity type)
-0.0036104966

4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLCB1
Gene (Entity type)
0.0032282213

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