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Nilotinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Nilotinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Nilotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Carbonic anhydrase 3 Protein (Entity type)	Ki
	Nilotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase ABL1 Protein (Entity type)	IC50
	Nilotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	0.0026428415
	Nilotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.003568488
	Nilotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RELB Gene (Entity type)	0.0028710682
	Nilotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NT5E Gene (Entity type)	0.0027579449
	Nilotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor beta Protein (Entity type)	Kd
	Nilotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Carbonic anhydrase 6 Protein (Entity type)	Ki
	Nilotinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	IC50
	Nilotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TSPAN13 Gene (Entity type)	-0.00287895

Nilotinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Carbonic anhydrase 3
Protein (Entity type)
Ki

Nilotinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase ABL1
Protein (Entity type)
IC50

Nilotinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PHLDA2
Gene (Entity type)
0.0026428415

Nilotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.003568488

Nilotinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RELB
Gene (Entity type)
0.0028710682

Nilotinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NT5E
Gene (Entity type)
0.0027579449

Nilotinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Platelet-derived growth factor receptor beta
Protein (Entity type)
Kd

Nilotinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Carbonic anhydrase 6
Protein (Entity type)
Ki

Nilotinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
IC50

Nilotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TSPAN13
Gene (Entity type)
-0.00287895

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