7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GABRP Gene (Entity type)	0.0055339993
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CA12 Gene (Entity type)	0.005118373
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LSM5 Gene (Entity type)	-0.0046266383
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Phenylbutazone Compound (Entity type)	0.3253485262393951
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ANXA3 Gene (Entity type)	-0.0054996787
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	-0.0075050523
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	imiquimod Compound (Entity type)	0.3031301498413086
lacitol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	0.2964529395103454
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HPGD Gene (Entity type)	-0.0048448974
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.0047177384

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GABRP
Gene (Entity type)
0.0055339993

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CA12
Gene (Entity type)
0.005118373

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LSM5
Gene (Entity type)
-0.0046266383

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Phenylbutazone
Compound (Entity type)
0.3253485262393951

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ANXA3
Gene (Entity type)
-0.0054996787

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ESR1
Gene (Entity type)
-0.0075050523

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
imiquimod
Compound (Entity type)
0.3031301498413086

lacitol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
0.2964529395103454

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HPGD
Gene (Entity type)
-0.0048448974

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.0047177384

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Knowledge Graph Assertions

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