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Eplerenone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Eplerenone's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Eplerenone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINB9 Gene (Entity type)	-0.0051346524
	Eplerenone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mineralocorticoid receptor Protein (Entity type)	IC50
	Eplerenone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	P3H2 Gene (Entity type)	0.004243637
	Eplerenone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TNFRSF11B Gene (Entity type)	0.0048637292
	Clinofibrate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Eplerenone Compound (Entity type)	0.2467056214809417
	Eplerenone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	-0.008681658
	Eplerenone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BEX1 Gene (Entity type)	-0.005846704
	Eplerenone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL5 Gene (Entity type)	-0.005272737
	Eplerenone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL13 Gene (Entity type)	0.00411873
	Cyclohexyl-(2-phenoxy-9H-purin-6-yl)-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Eplerenone Compound (Entity type)	0.1804983913898468

Eplerenone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINB9
Gene (Entity type)
-0.0051346524

Eplerenone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mineralocorticoid receptor
Protein (Entity type)
IC50

Eplerenone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
P3H2
Gene (Entity type)
0.004243637

Eplerenone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TNFRSF11B
Gene (Entity type)
0.0048637292

Clinofibrate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Eplerenone
Compound (Entity type)
0.2467056214809417

Eplerenone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
APOD
Gene (Entity type)
-0.008681658

Eplerenone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BEX1
Gene (Entity type)
-0.005846704

Eplerenone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL5
Gene (Entity type)
-0.005272737

Eplerenone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL13
Gene (Entity type)
0.00411873

Cyclohexyl-(2-phenoxy-9H-purin-6-yl)-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Eplerenone
Compound (Entity type)
0.1804983913898468

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