4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT17 Gene (Entity type)	-0.0048106895
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C2 Gene (Entity type)	0.00548817
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	MD-049 Compound (Entity type)	0.2639019191265106
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	-0.005088061
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C1 Gene (Entity type)	0.005034031
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A1 Gene (Entity type)	0.005499522
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NETO2 Gene (Entity type)	-0.0045781923
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GALNT1 Gene (Entity type)	-0.003928088
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GJA1 Gene (Entity type)	-0.004766369
4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Adenosine receptor A2a Protein (Entity type)	IC50

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT17
Gene (Entity type)
-0.0048106895

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C2
Gene (Entity type)
0.00548817

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
MD-049
Compound (Entity type)
0.2639019191265106

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAP7
Gene (Entity type)
-0.005088061

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C1
Gene (Entity type)
0.005034031

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A1
Gene (Entity type)
0.005499522

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NETO2
Gene (Entity type)
-0.0045781923

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GALNT1
Gene (Entity type)
-0.003928088

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GJA1
Gene (Entity type)
-0.004766369

4-(2-((7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino)ethyl)phenol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Adenosine receptor A2a
Protein (Entity type)
IC50

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