Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FHL1 Gene (Entity type)	-0.0042458894
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID103905024 Compound (Entity type)	0.263824999332428
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCB Gene (Entity type)	-0.004064376
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SORD Gene (Entity type)	0.0035906178
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OXTR Gene (Entity type)	0.0037974855
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPHA3 Gene (Entity type)	0.0036325217
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EMX2 Gene (Entity type)	-0.0045107487
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT1E Gene (Entity type)	0.0041310573
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IL6 Gene (Entity type)	-0.004452656
Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	-0.0040585315

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FHL1
Gene (Entity type)
-0.0042458894

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID103905024
Compound (Entity type)
0.263824999332428

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCB
Gene (Entity type)
-0.004064376

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SORD
Gene (Entity type)
0.0035906178

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OXTR
Gene (Entity type)
0.0037974855

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPHA3
Gene (Entity type)
0.0036325217

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EMX2
Gene (Entity type)
-0.0045107487

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT1E
Gene (Entity type)
0.0041310573

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IL6
Gene (Entity type)
-0.004452656

Rofecoxib; 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-Furanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
-0.0040585315

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