N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR7A2 Gene (Entity type)	-0.003076642
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Protein (Entity type)	IC50
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFD Gene (Entity type)	-0.004020072
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GABRP Gene (Entity type)	-0.0040343218
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PFKL Gene (Entity type)	0.0035028101
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BCHE Gene (Entity type)	0.0028964055
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCGB2A1 Gene (Entity type)	-0.0041437848
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Arbutin Compound (Entity type)	0.2884922623634338
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GLDC Gene (Entity type)	0.0028019228
N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100P Gene (Entity type)	-0.0036963536

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKR7A2
Gene (Entity type)
-0.003076642

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein (Entity type)
IC50

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFD
Gene (Entity type)
-0.004020072

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GABRP
Gene (Entity type)
-0.0040343218

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PFKL
Gene (Entity type)
0.0035028101

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BCHE
Gene (Entity type)
0.0028964055

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SCGB2A1
Gene (Entity type)
-0.0041437848

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Arbutin
Compound (Entity type)
0.2884922623634338

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GLDC
Gene (Entity type)
0.0028019228

N-(3-(N-(3-(3,5-dimethoxyphenylamino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100P
Gene (Entity type)
-0.0036963536

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