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Regorafenib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Regorafenib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Regorafenib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor beta Protein (Entity type)	IC50
	Regorafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PTN Gene (Entity type)	0.0037619919
	Regorafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	0.005319169
	Regorafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PYCR1 Gene (Entity type)	0.0037196856
	Regorafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	0.0053925817
	Regorafenib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Angiopoietin-1 receptor Protein (Entity type)	IC50
	Regorafenib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase B-raf Protein (Entity type)	IC50
	Regorafenib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mast/stem cell growth factor receptor Kit Protein (Entity type)	IC50
	Regorafenib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Metastasis from malignant tumor of colon Disease or Phenotype (Entity type)
	Regorafenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CIAO3 Gene (Entity type)	0.0041588424

Regorafenib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Platelet-derived growth factor receptor beta
Protein (Entity type)
IC50

Regorafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PTN
Gene (Entity type)
0.0037619919

Regorafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
0.005319169

Regorafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PYCR1
Gene (Entity type)
0.0037196856

Regorafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
0.0053925817

Regorafenib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Angiopoietin-1 receptor
Protein (Entity type)
IC50

Regorafenib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase B-raf
Protein (Entity type)
IC50

Regorafenib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mast/stem cell growth factor receptor Kit
Protein (Entity type)
IC50

Regorafenib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Metastasis from malignant tumor of colon
Disease or Phenotype (Entity type)

Regorafenib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CIAO3
Gene (Entity type)
0.0041588424

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