(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PGD Gene (Entity type)	-0.0065603717
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HOPX Gene (Entity type)	0.007179413
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB2 Gene (Entity type)	0.007529227
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5A Gene (Entity type)	-0.007099714
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SDC2 Gene (Entity type)	-0.0070236297
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	0.6105313897132874
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	-0.008031799
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIMM9 Gene (Entity type)	0.00687429
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSZ Gene (Entity type)	-0.007103044
(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TSPAN13 Gene (Entity type)	-0.0068125566

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PGD
Gene (Entity type)
-0.0065603717

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HOPX
Gene (Entity type)
0.007179413

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINB2
Gene (Entity type)
0.007529227

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5A
Gene (Entity type)
-0.007099714

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SDC2
Gene (Entity type)
-0.0070236297

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
0.6105313897132874

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
-0.008031799

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIMM9
Gene (Entity type)
0.00687429

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSZ
Gene (Entity type)
-0.007103044

(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TSPAN13
Gene (Entity type)
-0.0068125566

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Knowledge Graph Assertions

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