5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase A-Raf Protein (Entity type)	IC50
5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	RAF proto-oncogene serine/threonine-protein kinase Protein (Entity type)	IC50
5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase B-raf Protein (Entity type)	IC50

5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase A-Raf
Protein (Entity type)
IC50

5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
RAF proto-oncogene serine/threonine-protein kinase
Protein (Entity type)
IC50

5-[(1S,1aS,6aR)-1-(6-Trifluoromethyl-1H-benzoimidazol-2-yl)-1a,6a-dihydro-1H-6-oxa-cyclopropa[a]inden-3-yloxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase B-raf
Protein (Entity type)
IC50

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