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(-)-Nicotine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (-)-Nicotine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(-)-Nicotine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CIAO3 Gene (Entity type)	0.002916723
	(-)-Nicotine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRS1 Gene (Entity type)	0.0028404752
	(-)-Nicotine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CITED2 Gene (Entity type)	-0.0034121682
	(-)-Nicotine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCL19 Gene (Entity type)	-0.003448804
	(-)-Nicotine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GMDS Gene (Entity type)	0.0033504758
	(-)-Nicotine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STK26 Gene (Entity type)	-0.0033269413
	(-)-Nicotine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF5A Gene (Entity type)	0.0029980952
	(-)-Nicotine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC25A46 Gene (Entity type)	-0.0036910756
	(-)-Nicotine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC38A1 Gene (Entity type)	-0.0039495053
	Lisofylline Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(-)-Nicotine Compound (Entity type)	0.3110296726226806

(-)-Nicotine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CIAO3
Gene (Entity type)
0.002916723

(-)-Nicotine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RRS1
Gene (Entity type)
0.0028404752

(-)-Nicotine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CITED2
Gene (Entity type)
-0.0034121682

(-)-Nicotine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCL19
Gene (Entity type)
-0.003448804

(-)-Nicotine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GMDS
Gene (Entity type)
0.0033504758

(-)-Nicotine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STK26
Gene (Entity type)
-0.0033269413

(-)-Nicotine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF5A
Gene (Entity type)
0.0029980952

(-)-Nicotine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC25A46
Gene (Entity type)
-0.0036910756

(-)-Nicotine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC38A1
Gene (Entity type)
-0.0039495053

Lisofylline
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(-)-Nicotine
Compound (Entity type)
0.3110296726226806

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