N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COG7 Gene (Entity type)	0.0053441506
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TACSTD2 Gene (Entity type)	0.003609724
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100P Gene (Entity type)	0.004713996
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	0.0037827492
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein (Entity type)	IC50
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MERTK Gene (Entity type)	-0.002811895
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1H Gene (Entity type)	-0.0028077331
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID103905642 Compound (Entity type)	0.2530314028263092
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STC2 Gene (Entity type)	0.0033669495
N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	venetoclax Compound (Entity type)	0.2754608690738678

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COG7
Gene (Entity type)
0.0053441506

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TACSTD2
Gene (Entity type)
0.003609724

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100P
Gene (Entity type)
0.004713996

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
0.0037827492

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein (Entity type)
IC50

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MERTK
Gene (Entity type)
-0.002811895

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1H
Gene (Entity type)
-0.0028077331

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID103905642
Compound (Entity type)
0.2530314028263092

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STC2
Gene (Entity type)
0.0033669495

N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
venetoclax
Compound (Entity type)
0.2754608690738678

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Knowledge Graph Assertions

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