5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	0.0048572687
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	-0.0053695478
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	D Protein (Entity type)	Ki
Amphotericin-b Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	0.229332834482193
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCL20 Gene (Entity type)	-0.0040897317
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CAV2 Gene (Entity type)	0.0044551757
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTCH1 Gene (Entity type)	-0.0051678224
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	0.0064862277
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	pifithrin-mu Compound (Entity type)	0.4076519310474396
5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP1R3C Gene (Entity type)	0.0048973844