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Ro-318220 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Ro-318220's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Ro-318220 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ribosomal protein S6 kinase beta-1 Protein (Entity type)	IC50
	Ro-318220 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POLR2I Gene (Entity type)	0.009522702
	Ro-318220 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPIA Gene (Entity type)	0.011233789
	Ro-318220 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HEBP1 Gene (Entity type)	0.00983431
	Ro-318220 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H2AX Gene (Entity type)	-0.0123005565
	Ro-318220 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BNIP3L Gene (Entity type)	-0.010932079
	Ro-318220 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHST2 Gene (Entity type)	-0.011081049
	Ro-318220 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDH1 Gene (Entity type)	0.009549767
	Ro-318220 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SOX4 Gene (Entity type)	-0.01050862
	Ro-318220 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GFUS Gene (Entity type)	0.011469953

Ro-318220
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ribosomal protein S6 kinase beta-1
Protein (Entity type)
IC50

Ro-318220
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
POLR2I
Gene (Entity type)
0.009522702

Ro-318220
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPIA
Gene (Entity type)
0.011233789

Ro-318220
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HEBP1
Gene (Entity type)
0.00983431

Ro-318220
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H2AX
Gene (Entity type)
-0.0123005565

Ro-318220
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BNIP3L
Gene (Entity type)
-0.010932079

Ro-318220
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHST2
Gene (Entity type)
-0.011081049

Ro-318220
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDH1
Gene (Entity type)
0.009549767

Ro-318220
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SOX4
Gene (Entity type)
-0.01050862

Ro-318220
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GFUS
Gene (Entity type)
0.011469953

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