3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	-0.023800777
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP9 Gene (Entity type)	-0.007261819
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT5 Gene (Entity type)	0.0064291563
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.007834922
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ABLIM1 Gene (Entity type)	0.0057845693
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CSRP2 Gene (Entity type)	0.0053831595
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP53I3 Gene (Entity type)	0.0060044993
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPRY2 Gene (Entity type)	-0.010905079
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGR3 Gene (Entity type)	-0.009094814
Ulixertinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Compound (Entity type)	0.5911966562271118

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
-0.023800777

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP9
Gene (Entity type)
-0.007261819

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT5
Gene (Entity type)
0.0064291563

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IER3
Gene (Entity type)
-0.007834922

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ABLIM1
Gene (Entity type)
0.0057845693

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CSRP2
Gene (Entity type)
0.0053831595

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP53I3
Gene (Entity type)
0.0060044993

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPRY2
Gene (Entity type)
-0.010905079

3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EGR3
Gene (Entity type)
-0.009094814

Ulixertinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide
Compound (Entity type)
0.5911966562271118

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