8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ID1 Gene (Entity type)	0.008337044
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 2C Protein (Entity type)	Ki
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	l-bso Compound (Entity type)	0.2746513783931732
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TGIF1 Gene (Entity type)	0.008437282
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CH25H Gene (Entity type)	0.009474175
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIMM9 Gene (Entity type)	0.008355532
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL10 Gene (Entity type)	-0.009408547
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Gossypin Compound (Entity type)	0.2656089067459106
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	XIST Gene (Entity type)	-0.009246712
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CRIP1 Gene (Entity type)	-0.009690105

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ID1
Gene (Entity type)
0.008337044

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 2C
Protein (Entity type)
Ki

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
l-bso
Compound (Entity type)
0.2746513783931732

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TGIF1
Gene (Entity type)
0.008437282

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CH25H
Gene (Entity type)
0.009474175

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIMM9
Gene (Entity type)
0.008355532

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL10
Gene (Entity type)
-0.009408547

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Gossypin
Compound (Entity type)
0.2656089067459106

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
XIST
Gene (Entity type)
-0.009246712

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CRIP1
Gene (Entity type)
-0.009690105

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