1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5A Gene (Entity type)	-0.0072957864
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAGEA3 Gene (Entity type)	0.0073722918
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	WFDC2 Gene (Entity type)	-0.005931988
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	-0.006461353
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLA2G2A Gene (Entity type)	0.0056556277
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF1 Gene (Entity type)	0.0075761857
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	paclitaxel Compound (Entity type)	0.6558857560157776
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2C9 Protein (Entity type)	IC50
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 3A4 Protein (Entity type)	IC50
1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH2 Gene (Entity type)	-0.0053880154

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5A
Gene (Entity type)
-0.0072957864

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MAGEA3
Gene (Entity type)
0.0073722918

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
WFDC2
Gene (Entity type)
-0.005931988

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
-0.006461353

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLA2G2A
Gene (Entity type)
0.0056556277

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF1
Gene (Entity type)
0.0075761857

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
paclitaxel
Compound (Entity type)
0.6558857560157776

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2C9
Protein (Entity type)
IC50

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 3A4
Protein (Entity type)
IC50

1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDH2
Gene (Entity type)
-0.0053880154

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