6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	-0.025891291
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	0.018514711
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDK14 Gene (Entity type)	0.020933114
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FGB Gene (Entity type)	-0.0188332
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSPAN8 Gene (Entity type)	0.02433899
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPX3 Gene (Entity type)	-0.021404063
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	0.022164783
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFRD2 Gene (Entity type)	0.019054422
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DEFB1 Gene (Entity type)	-0.023258833
6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POSTN Gene (Entity type)	0.022426793

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
-0.025891291

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
0.018514711

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDK14
Gene (Entity type)
0.020933114

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FGB
Gene (Entity type)
-0.0188332

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSPAN8
Gene (Entity type)
0.02433899

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPX3
Gene (Entity type)
-0.021404063

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
0.022164783

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFRD2
Gene (Entity type)
0.019054422

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DEFB1
Gene (Entity type)
-0.023258833

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
POSTN
Gene (Entity type)
0.022426793

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