3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LSS Gene (Entity type)	0.016618926
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.029452905
SA-1921456 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	0.6087308526039124
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.012068827
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HERPUD1 Gene (Entity type)	0.016586073
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	CAM-9-027-3 Compound (Entity type)	0.6403160691261292
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SELENOW Gene (Entity type)	-0.009548249
R-96544 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	0.4383866190910339
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NSDHL Gene (Entity type)	0.021708582
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EXOSC4 Gene (Entity type)	-0.009120118

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LSS
Gene (Entity type)
0.016618926

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
0.029452905

SA-1921456
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
0.6087308526039124

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
-0.012068827

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HERPUD1
Gene (Entity type)
0.016586073

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
CAM-9-027-3
Compound (Entity type)
0.6403160691261292

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SELENOW
Gene (Entity type)
-0.009548249

R-96544
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
0.4383866190910339

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NSDHL
Gene (Entity type)
0.021708582

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EXOSC4
Gene (Entity type)
-0.009120118

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