N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	-0.003920851
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Hepatocyte growth factor receptor Protein (Entity type)	IC50
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOSL1 Gene (Entity type)	-0.0036802993
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT81 Gene (Entity type)	-0.004084918
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KIF14 Gene (Entity type)	-0.0037419705
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1E Gene (Entity type)	-0.0039124223
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Breakpoint cluster region protein Protein (Entity type)	Kd
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ME-0328 Compound (Entity type)	0.3361456096172333
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARMCX1 Gene (Entity type)	0.0032345199
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CLEC7A Gene (Entity type)	0.0032227351

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
-0.003920851

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Hepatocyte growth factor receptor
Protein (Entity type)
IC50

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOSL1
Gene (Entity type)
-0.0036802993

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT81
Gene (Entity type)
-0.004084918

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KIF14
Gene (Entity type)
-0.0037419705

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1E
Gene (Entity type)
-0.0039124223

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Breakpoint cluster region protein
Protein (Entity type)
Kd

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ME-0328
Compound (Entity type)
0.3361456096172333

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARMCX1
Gene (Entity type)
0.0032345199

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CLEC7A
Gene (Entity type)
0.0032227351

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