2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPM6B Gene (Entity type)	0.0051633185
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KCTD12 Gene (Entity type)	-0.004189386
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNA15 Gene (Entity type)	-0.0035591756
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TUBB2B Gene (Entity type)	0.003607248
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINA1 Gene (Entity type)	0.0037882105
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TUBB2A Gene (Entity type)	0.005535199
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ME1 Gene (Entity type)	-0.003846882
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP10 Gene (Entity type)	-0.0050504957
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1B10 Gene (Entity type)	0.005226134
adapalene Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole Compound (Entity type)	0.3748602569103241

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPM6B
Gene (Entity type)
0.0051633185

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KCTD12
Gene (Entity type)
-0.004189386

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNA15
Gene (Entity type)
-0.0035591756

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TUBB2B
Gene (Entity type)
0.003607248

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINA1
Gene (Entity type)
0.0037882105

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TUBB2A
Gene (Entity type)
0.005535199

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ME1
Gene (Entity type)
-0.003846882

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CASP10
Gene (Entity type)
-0.0050504957

2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1B10
Gene (Entity type)
0.005226134

adapalene
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
Compound (Entity type)
0.3748602569103241

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