1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP9 Gene (Entity type)	0.004004865
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NREP Gene (Entity type)	0.0032038963
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NEAT1 Gene (Entity type)	-0.0037460725
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPA2 Gene (Entity type)	0.0029898887
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DES Gene (Entity type)	-0.0033732636
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FN1 Gene (Entity type)	-0.0041583222
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POLR2I Gene (Entity type)	0.002870331
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.0032154091
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ABLIM1 Gene (Entity type)	-0.0033173277
1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GJA1 Gene (Entity type)	0.0035051098

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP9
Gene (Entity type)
0.004004865

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NREP
Gene (Entity type)
0.0032038963

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NEAT1
Gene (Entity type)
-0.0037460725

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPA2
Gene (Entity type)
0.0029898887

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DES
Gene (Entity type)
-0.0033732636

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FN1
Gene (Entity type)
-0.0041583222

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
POLR2I
Gene (Entity type)
0.002870331

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPINK1
Gene (Entity type)
-0.0032154091

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ABLIM1
Gene (Entity type)
-0.0033173277

1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenylsulfanyl-pyrrolidine-2-carboxylic acid (zofenopril)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GJA1
Gene (Entity type)
0.0035051098

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Knowledge Graph Assertions

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