(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMG20B Gene (Entity type)	-0.008113006
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL13 Gene (Entity type)	-0.010243812
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLF5 Gene (Entity type)	-0.008446371
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP1B1 Gene (Entity type)	0.009339976
[2-(4-Benzyl-phenoxy)-ethyl]-diethyl-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	0.2223654240369796
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NT5E Gene (Entity type)	0.013448516
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STUB1 Gene (Entity type)	-0.010163119
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FBXO11 Gene (Entity type)	-0.008427022
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TENT5A Gene (Entity type)	-0.010214475
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FADS2 Gene (Entity type)	0.010902012

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMG20B
Gene (Entity type)
-0.008113006

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL13
Gene (Entity type)
-0.010243812

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLF5
Gene (Entity type)
-0.008446371

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP1B1
Gene (Entity type)
0.009339976

[2-(4-Benzyl-phenoxy)-ethyl]-diethyl-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
0.2223654240369796

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NT5E
Gene (Entity type)
0.013448516

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STUB1
Gene (Entity type)
-0.010163119

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FBXO11
Gene (Entity type)
-0.008427022

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TENT5A
Gene (Entity type)
-0.010214475

(4,5-bis(4-methoxyphenyl)thiazol-2-yl)(4-methylpiperazin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FADS2
Gene (Entity type)
0.010902012

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