4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADD3 Gene (Entity type)	-0.023871556
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BGN Gene (Entity type)	-0.021446595
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMSB15A Gene (Entity type)	0.019616691
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT14 Gene (Entity type)	-0.023895705
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C2 Gene (Entity type)	0.02413518
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPD52 Gene (Entity type)	-0.023391163
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SFRP4 Gene (Entity type)	-0.022791898
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GJA1 Gene (Entity type)	0.02170003
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM5A Gene (Entity type)	-0.021560686
4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PEG3 Gene (Entity type)	0.02163666

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADD3
Gene (Entity type)
-0.023871556

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BGN
Gene (Entity type)
-0.021446595

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMSB15A
Gene (Entity type)
0.019616691

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT14
Gene (Entity type)
-0.023895705

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C2
Gene (Entity type)
0.02413518

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TPD52
Gene (Entity type)
-0.023391163

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SFRP4
Gene (Entity type)
-0.022791898

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GJA1
Gene (Entity type)
0.02170003

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM5A
Gene (Entity type)
-0.021560686

4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PEG3
Gene (Entity type)
0.02163666

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