9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100P Gene (Entity type)	0.013112506
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FABP5 Gene (Entity type)	-0.010977461
GW-6471 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	0.2927185297012329
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PSTPIP2 Gene (Entity type)	-0.009263391
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT2A Gene (Entity type)	-0.00935007
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CAV1 Gene (Entity type)	-0.00906558
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1M Gene (Entity type)	-0.012195283
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PPP2R5E Gene (Entity type)	-0.01075846
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	IC50
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1F Gene (Entity type)	-0.010749011

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100P
Gene (Entity type)
0.013112506

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FABP5
Gene (Entity type)
-0.010977461

GW-6471
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
0.2927185297012329

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PSTPIP2
Gene (Entity type)
-0.009263391

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT2A
Gene (Entity type)
-0.00935007

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CAV1
Gene (Entity type)
-0.00906558

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1M
Gene (Entity type)
-0.012195283

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PPP2R5E
Gene (Entity type)
-0.01075846

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
IC50

9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1F
Gene (Entity type)
-0.010749011

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