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Selumetinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Selumetinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Selumetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMT1A Gene (Entity type)	0.0066654184
	Selumetinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Uncharacterized protein FLJ45252 Protein (Entity type)	Kd
	Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MLPH Gene (Entity type)	-0.009423001
	Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGR1 Gene (Entity type)	-0.009279698
	Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP5 Gene (Entity type)	-0.01000382
	Selumetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFIT1 Gene (Entity type)	0.007022045
	Selumetinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Trametinib Compound (Entity type)	0.921485185623169
	Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA1 Gene (Entity type)	-0.015397161
	Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STX1A Gene (Entity type)	-0.009483574
	PD-325901 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Selumetinib Compound (Entity type)	0.9218671321868896

Selumetinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMT1A
Gene (Entity type)
0.0066654184

Selumetinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Uncharacterized protein FLJ45252
Protein (Entity type)
Kd

Selumetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MLPH
Gene (Entity type)
-0.009423001

Selumetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EGR1
Gene (Entity type)
-0.009279698

Selumetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP5
Gene (Entity type)
-0.01000382

Selumetinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFIT1
Gene (Entity type)
0.007022045

Selumetinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Trametinib
Compound (Entity type)
0.921485185623169

Selumetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHLDA1
Gene (Entity type)
-0.015397161

Selumetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STX1A
Gene (Entity type)
-0.009483574

PD-325901
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Selumetinib
Compound (Entity type)
0.9218671321868896

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