Selumetinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Selumetinib's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
Selumetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMT1A Gene (Entity type)	0.0066654184
Selumetinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Uncharacterized protein FLJ45252 Protein (Entity type)	Kd
Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MLPH Gene (Entity type)	-0.009423001
Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGR1 Gene (Entity type)	-0.009279698
Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP5 Gene (Entity type)	-0.01000382
Selumetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFIT1 Gene (Entity type)	0.007022045
Selumetinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Trametinib Compound (Entity type)	0.921485185623169
Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA1 Gene (Entity type)	-0.015397161
Selumetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STX1A Gene (Entity type)	-0.009483574
PD-325901 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Selumetinib Compound (Entity type)	0.9218671321868896

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.