1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.013115215
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	-0.010563065
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNNT1 Gene (Entity type)	-0.010238577
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CNPY3 Gene (Entity type)	0.009968249
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	XIST Gene (Entity type)	-0.014909573
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF586 Gene (Entity type)	-0.013758756
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin G/H synthase 2 Protein (Entity type)	IC50
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HPGD Gene (Entity type)	-0.011966445
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PIP Gene (Entity type)	0.010920216
1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BMP2 Gene (Entity type)	0.010213722

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
0.013115215

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
-0.010563065

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNNT1
Gene (Entity type)
-0.010238577

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CNPY3
Gene (Entity type)
0.009968249

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
XIST
Gene (Entity type)
-0.014909573

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZNF586
Gene (Entity type)
-0.013758756

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin G/H synthase 2
Protein (Entity type)
IC50

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HPGD
Gene (Entity type)
-0.011966445

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PIP
Gene (Entity type)
0.010920216

1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BMP2
Gene (Entity type)
0.010213722

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