(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ANXA1 Gene (Entity type)	-0.003393274
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endothelin-1 receptor Protein (Entity type)	IC50
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFRSF12A Gene (Entity type)	-0.0040142173
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.0049275113
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STK26 Gene (Entity type)	0.0038196098
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NEFH Gene (Entity type)	0.0037993637
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SELENOP Gene (Entity type)	0.004491329
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.0049909726
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GTSE1 Gene (Entity type)	0.00333261
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	bucladesine Compound (Entity type)	0.2706217467784881