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TAK-580 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TAK-580's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	TAK-580 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL2 Gene (Entity type)	0.0061081783
	TAK-580 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.007183729
	TAK-580 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase B-raf Protein (Entity type)	IC50
	TAK-580 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPSAB1 Gene (Entity type)	-0.005525554
	TAK-580 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCRG1 Gene (Entity type)	0.0054364973
	cholic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	TAK-580 Compound (Entity type)	0.564582347869873
	Loxoprofen Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	TAK-580 Compound (Entity type)	0.4282096326351166
	TAK-580 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ID4 Gene (Entity type)	0.0060816533
	TAK-580 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDC20 Gene (Entity type)	0.0059002344
	TAK-580 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GABRP Gene (Entity type)	0.0048479787

TAK-580
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL2
Gene (Entity type)
0.0061081783

TAK-580
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
0.007183729

TAK-580
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase B-raf
Protein (Entity type)
IC50

TAK-580
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TPSAB1
Gene (Entity type)
-0.005525554

TAK-580
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCRG1
Gene (Entity type)
0.0054364973

cholic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
TAK-580
Compound (Entity type)
0.564582347869873

Loxoprofen
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
TAK-580
Compound (Entity type)
0.4282096326351166

TAK-580
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ID4
Gene (Entity type)
0.0060816533

TAK-580
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDC20
Gene (Entity type)
0.0059002344

TAK-580
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GABRP
Gene (Entity type)
0.0048479787

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