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acalabrutinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View acalabrutinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	acalabrutinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Duvelisib Compound (Entity type)	0.3202677965164184
	acalabrutinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	REG1A Gene (Entity type)	-0.004514335
	acalabrutinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCGB2A2 Gene (Entity type)	0.004774329
	Copanlisib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	acalabrutinib Compound (Entity type)	0.2795240581035614
	acalabrutinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SMC1A Gene (Entity type)	-0.0043876427
	acalabrutinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytoplasmic tyrosine-protein kinase BMX Protein (Entity type)	IC50
	acalabrutinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	F3 Gene (Entity type)	-0.005082877
	acalabrutinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GEM Gene (Entity type)	-0.005504546
	acalabrutinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BTBD3 Gene (Entity type)	0.0045911246
	acalabrutinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Rolipram Compound (Entity type)	0.2938229441642761

acalabrutinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Duvelisib
Compound (Entity type)
0.3202677965164184

acalabrutinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
REG1A
Gene (Entity type)
-0.004514335

acalabrutinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCGB2A2
Gene (Entity type)
0.004774329

Copanlisib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
acalabrutinib
Compound (Entity type)
0.2795240581035614

acalabrutinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SMC1A
Gene (Entity type)
-0.0043876427

acalabrutinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytoplasmic tyrosine-protein kinase BMX
Protein (Entity type)
IC50

acalabrutinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
F3
Gene (Entity type)
-0.005082877

acalabrutinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GEM
Gene (Entity type)
-0.005504546

acalabrutinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BTBD3
Gene (Entity type)
0.0045911246

acalabrutinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Rolipram
Compound (Entity type)
0.2938229441642761

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