(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Receptor-type tyrosine-protein kinase FLT3 Protein (Entity type)	IC50
(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Aurora kinase B Protein (Entity type)	Kd
(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Aurora kinase A Protein (Entity type)	Kd
(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase Chk1 Protein (Entity type)	IC50

(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Receptor-type tyrosine-protein kinase FLT3
Protein (Entity type)
IC50

(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Aurora kinase B
Protein (Entity type)
Kd

(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Aurora kinase A
Protein (Entity type)
Kd

(+)-3-((tert-butylamino)(pyridin-2-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase Chk1
Protein (Entity type)
IC50

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Knowledge Graph Assertions

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