AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NMU Gene (Entity type)	-0.004629283
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.006078008
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Extracellular calcium-sensing receptor Protein (Entity type)	EC50
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.008035838
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OAS3 Gene (Entity type)	0.004868827
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.004929819
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 5 Protein (Entity type)	-
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINE2 Gene (Entity type)	0.0046762936
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRTN3 Gene (Entity type)	-0.004920187
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	0.0050207837

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NMU
Gene (Entity type)
-0.004629283

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
-0.006078008

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Extracellular calcium-sensing receptor
Protein (Entity type)
EC50

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.008035838

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OAS3
Gene (Entity type)
0.004868827

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
A2M
Gene (Entity type)
0.004929819

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 5
Protein (Entity type)
-

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINE2
Gene (Entity type)
0.0046762936

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRTN3
Gene (Entity type)
-0.004920187

AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
0.0050207837

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Knowledge Graph Assertions

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