(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT5 Gene (Entity type)	-0.003597454
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	-0.0029906495
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NIBAN1 Gene (Entity type)	0.0035743366
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Matrix metalloproteinase-17 Protein (Entity type)	IC50
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Disintegrin and metalloproteinase domain-containing protein 9 Protein (Entity type)	IC50
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOC1 Gene (Entity type)	-0.0028451914
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	A disintegrin and metalloproteinase with thrombospondin motifs 4 Protein (Entity type)	IC50
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL2 Gene (Entity type)	-0.0032094878
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Disintegrin and metalloproteinase domain-containing protein 12 Protein (Entity type)	IC50
(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Macrophage metalloelastase Protein (Entity type)	Ki