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Berberine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Berberine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Berberine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HERPUD1 Gene (Entity type)	0.005452728
	Berberine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GAD1 Gene (Entity type)	0.0042698532
	Berberine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	E2F2 Gene (Entity type)	0.0070000733
	Berberine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLXNC1 Gene (Entity type)	-0.004917026
	Berberine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RTN1 Gene (Entity type)	-0.0046769674
	Berberine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC5A6 Gene (Entity type)	0.004290546
	2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-4,4-dimethyl-4H-isoquinoline-1,3-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Berberine Compound (Entity type)	0.2462315261363983
	Berberine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PEG10 Gene (Entity type)	-0.0077073523
	Tasquinimod Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Berberine Compound (Entity type)	0.4751890003681183
	Berberine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARNT2 Gene (Entity type)	-0.004925508

Berberine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HERPUD1
Gene (Entity type)
0.005452728

Berberine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GAD1
Gene (Entity type)
0.0042698532

Berberine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
E2F2
Gene (Entity type)
0.0070000733

Berberine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLXNC1
Gene (Entity type)
-0.004917026

Berberine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RTN1
Gene (Entity type)
-0.0046769674

Berberine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC5A6
Gene (Entity type)
0.004290546

2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-4,4-dimethyl-4H-isoquinoline-1,3-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Berberine
Compound (Entity type)
0.2462315261363983

Berberine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PEG10
Gene (Entity type)
-0.0077073523

Tasquinimod
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Berberine
Compound (Entity type)
0.4751890003681183

Berberine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ARNT2
Gene (Entity type)
-0.004925508

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