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amitriptyline (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View amitriptyline's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	amitriptyline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYBA Gene (Entity type)	-0.0056220754
	amitriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.009046053
	amitriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNAJA3 Gene (Entity type)	0.007886824
	amitriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP51A1 Gene (Entity type)	0.008936267
	amitriptyline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M2 Protein (Entity type)	Ki
	amitriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LDLR Gene (Entity type)	0.007811405
	amitriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHI3L1 Gene (Entity type)	0.009591922
	amitriptyline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	-0.004768499
	amitriptyline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 2B Protein (Entity type)	Ki
	amitriptyline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLF10 Gene (Entity type)	-0.0049557793

amitriptyline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYBA
Gene (Entity type)
-0.0056220754

amitriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHCR7
Gene (Entity type)
0.009046053

amitriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNAJA3
Gene (Entity type)
0.007886824

amitriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP51A1
Gene (Entity type)
0.008936267

amitriptyline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M2
Protein (Entity type)
Ki

amitriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LDLR
Gene (Entity type)
0.007811405

amitriptyline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHI3L1
Gene (Entity type)
0.009591922

amitriptyline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
-0.004768499

amitriptyline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 2B
Protein (Entity type)
Ki

amitriptyline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLF10
Gene (Entity type)
-0.0049557793

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