Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	-0.005899872
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Clobetasol propionate Compound (Entity type)	0.6333395838737488
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM158 Gene (Entity type)	-0.007408827
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSC22D3 Gene (Entity type)	0.02020053
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Seborrheic dermatitis Disease or Phenotype (Entity type)
amcinonide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	0.5634809136390686
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PER1 Gene (Entity type)	0.008088374
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GLUL Gene (Entity type)	0.008014821
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	-0.006100945
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NFKBIA Gene (Entity type)	0.009613327