2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Carbamazepine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	0.5419416427612305
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRS2 Gene (Entity type)	-0.0033135316
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCOLN1 Gene (Entity type)	-0.003345461
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Carbamazepine Compound (Entity type)	0.5419416427612305
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-1D adrenergic receptor Protein (Entity type)	Ki
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Schizophrenia Disease or Phenotype (Entity type)
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COL11A1 Gene (Entity type)	-0.0036440915
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	0.004685644
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent noradrenaline transporter Protein (Entity type)	Ki
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LTF Gene (Entity type)	0.0060961815

Carbamazepine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
0.5419416427612305

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IRS2
Gene (Entity type)
-0.0033135316

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MCOLN1
Gene (Entity type)
-0.003345461

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Carbamazepine
Compound (Entity type)
0.5419416427612305

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-1D adrenergic receptor
Protein (Entity type)
Ki

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Schizophrenia
Disease or Phenotype (Entity type)

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COL11A1
Gene (Entity type)
-0.0036440915

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
0.004685644

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent noradrenaline transporter
Protein (Entity type)
Ki

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LTF
Gene (Entity type)
0.0060961815

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