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(+/-)-Gossypol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (+/-)-Gossypol's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(+/-)-Gossypol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC38A1 Gene (Entity type)	0.0064372583
	Artesunate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(+/-)-Gossypol Compound (Entity type)	0.4673923254013061
	(+/-)-Gossypol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSC22D3 Gene (Entity type)	0.007749325
	(+/-)-Gossypol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH1A1 Gene (Entity type)	-0.003942456
	(+/-)-Gossypol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Apoptosis regulator Bcl-2 Protein (Entity type)	Ki
	(+/-)-Gossypol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MTUS1 Gene (Entity type)	-0.003719864
	(+/-)-Gossypol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Induced myeloid leukemia cell differentiation protein Mcl-1 Protein (Entity type)	Ki
	Amuvatinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(+/-)-Gossypol Compound (Entity type)	0.3992793262004852
	(+/-)-Gossypol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	0.006860025
	(+/-)-Gossypol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SHMT2 Gene (Entity type)	0.0073010353

(+/-)-Gossypol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC38A1
Gene (Entity type)
0.0064372583

Artesunate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(+/-)-Gossypol
Compound (Entity type)
0.4673923254013061

(+/-)-Gossypol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSC22D3
Gene (Entity type)
0.007749325

(+/-)-Gossypol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDH1A1
Gene (Entity type)
-0.003942456

(+/-)-Gossypol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Apoptosis regulator Bcl-2
Protein (Entity type)
Ki

(+/-)-Gossypol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MTUS1
Gene (Entity type)
-0.003719864

(+/-)-Gossypol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Induced myeloid leukemia cell differentiation protein Mcl-1
Protein (Entity type)
Ki

Amuvatinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(+/-)-Gossypol
Compound (Entity type)
0.3992793262004852

(+/-)-Gossypol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
0.006860025

(+/-)-Gossypol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SHMT2
Gene (Entity type)
0.0073010353

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