(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
SQ-22536 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	0.2824571430683136
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	UPP1 Gene (Entity type)	-0.0032414983
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI6 Gene (Entity type)	-0.003604086
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GBP1 Gene (Entity type)	0.0032738447
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFBI Gene (Entity type)	-0.0033332617
Phenothiazine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	0.440803974866867
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A7 Gene (Entity type)	0.0032648714
N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-indacen-8-yl)-ethyl]-propionamide(S)-(-)-22b Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	0.3605490922927856
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCL2 Gene (Entity type)	0.005183935
HO-013 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid Compound (Entity type)	0.362461119890213

SQ-22536
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
0.2824571430683136

(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
UPP1
Gene (Entity type)
-0.0032414983

(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI6
Gene (Entity type)
-0.003604086

(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GBP1
Gene (Entity type)
0.0032738447

(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFBI
Gene (Entity type)
-0.0033332617

Phenothiazine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
0.440803974866867

(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100A7
Gene (Entity type)
0.0032648714

N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-indacen-8-yl)-ethyl]-propionamide(S)-(-)-22b
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
0.3605490922927856

(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCL2
Gene (Entity type)
0.005183935

HO-013
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(2S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
Compound (Entity type)
0.362461119890213

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