(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Hepatocyte growth factor receptor Protein (Entity type)	IC50
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLPI Gene (Entity type)	-0.0043141
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.006353589
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein-tyrosine kinase 2-beta Protein (Entity type)	Ki
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDOB Gene (Entity type)	0.0044351094
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	0.0068736174
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	XCL1 Gene (Entity type)	-0.0039577824
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RNASE1 Gene (Entity type)	-0.006089659
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF1 Gene (Entity type)	0.0073191617
(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.006135438

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Hepatocyte growth factor receptor
Protein (Entity type)
IC50

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLPI
Gene (Entity type)
-0.0043141

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
0.006353589

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Protein-tyrosine kinase 2-beta
Protein (Entity type)
Ki

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDOB
Gene (Entity type)
0.0044351094

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
0.0068736174

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
XCL1
Gene (Entity type)
-0.0039577824

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RNASE1
Gene (Entity type)
-0.006089659

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF1
Gene (Entity type)
0.0073191617

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
0.006135438

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