Mitotane (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Mitotane's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
Mitotane Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent noradrenaline transporter Protein (Entity type)	IC50
Mitotane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNAS Gene (Entity type)	-0.006462011
Mitotane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	0.0069307396
Mitotane Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Carcinoma in situ of adrenal cortex Disease or Phenotype (Entity type)
Mitotane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	-0.00516591
Mitotane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CEACAM6 Gene (Entity type)	-0.0050074486
Mitotane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	VCAM1 Gene (Entity type)	0.0050717634
Mitotane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH1A1 Gene (Entity type)	-0.009247165
Mitotane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP9 Gene (Entity type)	0.0068587153
Mitotane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAC8 Gene (Entity type)	-0.006918272

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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