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spironolactone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View spironolactone's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	spironolactone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GOLGA8A Gene (Entity type)	0.0036339404
	spironolactone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	USP32P2 Gene (Entity type)	0.0029724408
	spironolactone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GOLGA8H Gene (Entity type)	0.0029826462
	spironolactone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	XIST Gene (Entity type)	-0.0040840777
	spironolactone Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Hyperaldosteronism Disease or Phenotype (Entity type)
	spironolactone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI2 Gene (Entity type)	-0.005418374
	spironolactone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	0.004466495
	spironolactone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NTS Gene (Entity type)	-0.003903358
	spironolactone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COL4A1 Gene (Entity type)	0.003048058
	spironolactone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	sodium-gualenate Compound (Entity type)	0.2986250519752502

spironolactone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GOLGA8A
Gene (Entity type)
0.0036339404

spironolactone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
USP32P2
Gene (Entity type)
0.0029724408

spironolactone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GOLGA8H
Gene (Entity type)
0.0029826462

spironolactone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
XIST
Gene (Entity type)
-0.0040840777

spironolactone
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Hyperaldosteronism
Disease or Phenotype (Entity type)

spironolactone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TFPI2
Gene (Entity type)
-0.005418374

spironolactone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
0.004466495

spironolactone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NTS
Gene (Entity type)
-0.003903358

spironolactone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COL4A1
Gene (Entity type)
0.003048058

spironolactone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
sodium-gualenate
Compound (Entity type)
0.2986250519752502

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