4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
AZD-3514 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	0.3909867703914642
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFI6 Gene (Entity type)	0.0066263755
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SFTPB Gene (Entity type)	-0.005647835
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LPCAT1 Gene (Entity type)	-0.004261546
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCLAF Gene (Entity type)	0.0062167277
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT14 Gene (Entity type)	0.007808549
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF586 Gene (Entity type)	-0.00654458
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM13 Gene (Entity type)	-0.004934091
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NFATC3 Gene (Entity type)	-0.0043241708
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Acute Promyelocytic Leukemia Disease or Phenotype (Entity type)

AZD-3514
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
0.3909867703914642

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFI6
Gene (Entity type)
0.0066263755

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SFTPB
Gene (Entity type)
-0.005647835

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LPCAT1
Gene (Entity type)
-0.004261546

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCLAF
Gene (Entity type)
0.0062167277

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT14
Gene (Entity type)
0.007808549

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZNF586
Gene (Entity type)
-0.00654458

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM13
Gene (Entity type)
-0.004934091

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NFATC3
Gene (Entity type)
-0.0043241708

4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Acute Promyelocytic Leukemia
Disease or Phenotype (Entity type)

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Knowledge Graph Assertions

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