3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 3 subunit alpha Protein (Entity type)	IC50
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 7 subunit alpha Protein (Entity type)	IC50
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 8 subunit alpha Protein (Entity type)	IC50
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 9 subunit alpha Protein (Entity type)	IC50
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 2 subunit alpha Protein (Entity type)	IC50
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	High affinity choline transporter 1 Protein (Entity type)	Ki
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 4 subunit alpha Protein (Entity type)	IC50
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 5 subunit alpha Protein (Entity type)	IC50
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	Ki
3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 1 subunit alpha Protein (Entity type)	IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 3 subunit alpha
Protein (Entity type)
IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 7 subunit alpha
Protein (Entity type)
IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 8 subunit alpha
Protein (Entity type)
IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 9 subunit alpha
Protein (Entity type)
IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 2 subunit alpha
Protein (Entity type)
IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
High affinity choline transporter 1
Protein (Entity type)
Ki

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 4 subunit alpha
Protein (Entity type)
IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 5 subunit alpha
Protein (Entity type)
IC50

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
Ki

3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 1 subunit alpha
Protein (Entity type)
IC50

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