1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase 17A Protein (Entity type)	IC50
1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase TBK1 Protein (Entity type)	IC50
1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Protein (Entity type)	IC50

1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase 17A
Protein (Entity type)
IC50

1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase TBK1
Protein (Entity type)
IC50

1-(4-{(1R)-1-[2-({6-[1-(Cyclobutylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Protein (Entity type)
IC50

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